Development and evaluation of film coated tablets of letrozole (Paperback)

Development and evaluation of film coated tablets of letrozole (Paperback) Focuses on the formulation of letrozole, a non-steroidal aromatase inhibitor, as an anti-estrogen drug Aims to achieve an in-vitro dissolution profile similar to the reference product Targets development of a dosage form for drug application to abbreviated new drug application (ANDA) Designed for immediate drug delivery to alter pharmacokinetics and pharmacodynamics effectively Seeks rapid onset of action, addressing limitations of conventional tablets in releasing medication quickly Suitable for drugs with long half-lives and high bioavailability, enhancing immediate-release dosage forms Involves creating a stable, bio-equivalent oral immediate-release tablet of letrozole to help prevent breast cancer relapse